Lakeshore Examination of Activity and Disability Exercise Response Study "LEADERS"

Recruiting

Phase N/A Results N/A

Trial Description

This study will examine the effectiveness of two types of group exercise classes on the health and functional status in inactive adults age 18-65 with neurological conditions including Multiple Sclerosis, stroke, and spinal cord injury (SCI). Participants will be randomly assigned to one of three groups; Movement to Music, Adapted Yoga, or a waitlist group who will complete a home-based exercise intervention of either Movement to Music or Adapted Yoga.

Conditions

Interventions

  • Movement to Music Behavioral
    Other Names: M2M
    ARM 1: Kind: Experimental
    Label: Movement to Music
    Description: The Movement to Music classes are composed of a set of exercises tailored to the specific needs and capabilities of each target group. The class will consist of and aerobic component and a strength component performed to varying music tempos. All movements will be choreographed by qualified dance instructors.
  • Adapted Yoga Behavioral
    ARM 1: Kind: Experimental
    Label: Adapted Yoga
    Description: Yoga classes will consist of postures adapted by qualified yoga instructors who have extensive experience in disability.

Outcomes

Type Measure Time Frame Safety Issue
Primary Cardiorespiratory Fitness as measured by sub-maximal VO2 12 weeks
Primary Pain as measured by PROMIS Pain Interference Short Form 8a 12 weeks
Primary Fatigue as measured by PROMIS Fatigue Short Form 8a 12 weeks
Primary Loneliness as measured by the Three-Item Loneliness Scale 12 weeks
Primary Grip Strength as measured by hand grip dynamometer 12 weeks
Primary Strength as measured by Biodex System 3 Multijoint dynamometer 12 weeks
Primary Balance as measured by the Timed Up and Go 12 weeks
Primary Balance as measured by Biodex Limits of Stability 12 weeks
Primary Balance as measured by Repeated Chair Stands 12 weeks
Secondary Health Biomarkers as measured by blood analysis (insulin) 12 weeks
Secondary Health Biomarkers as measured by blood analysis (lipids) 12 weeks
Secondary Health Biomarkers as measured by blood analysis (fasting glucose) 12 weeks
Secondary Blood pressure 12 weeks
Secondary Anthropometric measurements (weight) 12 weeks
Secondary Circumference measurements to be reported as composite ratios (waist circumference, hip circumference, neck circumference) 12 weeks
Secondary Physical Function with Mobility Aid as measured by PROMIS Physical Function with Mobility Aid 455b 12 weeks
Secondary Anxiety as measured by PROMIS Emotional Distress-Anxiety Short Form 8a 12 weeks
Secondary Depression as measured by PROMIS Emotional Distress-Depression Short Form 8a 12 weeks
Secondary Sleep Disturbance as measured by PROMIS Sleep Disturbance Short Form 8a 12 weeks
Secondary Ability to participate in social roles and activities as measured by PROMIS Ability to Participate in Social Roles and Activities Short Form 8a 12 weeks
Secondary Nutrition Self-Efficacy as measured by the Nutrition Self-Efficacy Scale 12 weeks
Secondary Physical Exercise Self-Efficacy as measured by the Physical Exercise Self Efficacy Scale 12 weeks
Secondary PROMIS Pain Intensity Short Form 12 Weeks

Sponsors