LAA Excision With AF Ablation Versus Oral Anticoagulants for Secondary Prevention of Stroke "5A"


Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

- 18-80 years
- Have documented AF episodes
- The occurrence of ischemic stroke, TIA or systemic thromboembolism at least one month before enrollment
- Capable of understanding and signing the CRF

Exclusion Criteria

- Reversible AF
- Modified Rankin score ≥4
- Having a history of rheumatic, severe valvular heart disease or heart valve replacement
- Having symptomatic carotid artery disease
- Having another disease which requires lifelong warfarin therapy
- Medical conditions limiting expected survival to <1 year
- Women of childbearing potential (unless post-menopausal or surgically sterile)
- Participation in any other clinical mortality trial
- Unable to give informed consent