Intraventricular Hemorrhage Thrombolysis Trial "ITT"

Completed

Phase 2 Results

Eligibility Criteria

Inclusion Criteria

Patients with CT-confirmed IVH who are 12-24 hours post-bleed, whose hematoma size is stable, and who have received a post-IVH catheter CT scan are eligible for this study.

Exclusion Criteria

Patients who have an infratentorial bleed, a supratentorial bleed > 30 cc, a suspected unclipped aneurysm or arteriovenous malformation, any severe complicating illness, confounding cardiovascular parameters, or active internal bleeding, who require heparin > 10,000 U/day, who take coumadin, who are allergic to r-TPA, or who are pregnant will be excluded from the study.