Intravenous Thrombolysis Plus Hypothermia for Acute Treatment of Ischemic Stroke

Completed

Phase 1 Results

References

Publications

  • Hemmen TM, Raman R, Guluma KZ, Meyer BC, Gomes JA, Cruz-Flores S, Wijman CA, Rapp KS, Grotta JC, Lyden PD; ICTuS-L Investigators. Intravenous thrombolysis plus hypothermia for acute treatment of ischemic stroke (ICTuS-L): final results. Stroke. 2010 Oct;41(10):2265-70. Epub 2010 Aug 19. Pubmed ID:20724711
  • Lyden Patrick D., Allgren Robin L., Ng Ken, Akins Paul, Meyer Brett, Fahmi Al-Sanani, Lutsep Helmi, Dobak John, Matsubara Bradley S., Zivin Justin; Intravascular Cooling in the Treatment of Stroke (ICTuS): Early Clinical Experience: Journal of Stroke and Cerebrovascular Diseases, Vol. 14, No. 3 (May - June), 2005: pp 107 - 114.
  • Guluma KZ, Hemmen TM, Olsen SE, Rapp KS, Lyden PD. A trial of therapeutic hypothermia via endovascular approach in awake patients with acute ischemic stroke: methodology. Acad Emerg Med. 2006 Aug;13(8):820-7. Epub 2006 Jun 9. Pubmed ID:16766740
  • Hemmen TM, Lyden PD. Induced hypothermia for acute stroke. Stroke. 2007 Feb;38(2 Suppl):794-9. Review. Pubmed ID:17261741

Sources for Trial Information