Intravenous Nimodipine in Acute Ischemic Stroke

Completed

Phase N/A Results

Trial Description

To study the efficacy of nimodipine in the treatment of acute ischemic stroke.

Interventions

  • Nimodipine (NimotopĀ®)Drug
    Intervention Desc: Calcium channel blocker (L-type calcium channels)

Trial Design

Randomized, double-blind, placebo-controlled trial of 164 patients.

Patient Involvement

Patients were randomized to receive intravenous nimodipine (day 1-10: 2mg/hr, day 11-6 months:180mg/day orally) or placebo.

Outcomes

Type Measure Time Frame Safety Issue
Primary Toronto Stroke Scale, functional disability, and deaths during 1 year follow-up period.

Sponsors

Bayer AG