Intravenous Heparin for the Prevention of Stroke Progression in Acute Partial Stable Stroke.


Phase N/A Results

Trial Description

To evaluate the efficacy of intravenous heparin in the prevention of stroke progression or death in patients with acute partial stable stroke.


Trial Design

Randomized, double-blind, placebo-controlled trial of 225 patients at 3 centers.

Patient Involvement

Patients were randomized to receive intravenous heparin or placebo for 7 days. Follow-up period of 1 year.


Type Measure Time Frame Safety Issue
Primary Degree of stroke progression as determined by changes in focal neurologic score, or number of deaths during 7-day treatment period.


Canadian and Ontario Heart and Stroke Foundation, Hamilton Civic Hospitals Research Fund.