Intraoperative Hypothermia for Aneurysm Surgery Trial, Part 2 "IHAST2"


Phase N/A Results

Summary of Purpose

To investigate the neuroprotective efficacy of mild intraoperative hypothermia (target core temperature 33°C) during open craniotomies performed to clip intracranial aneurysms.

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 13 August 2008.

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Start Date First Received 1st Completion Completion Verification Results

Trial Basics



  • National Institute for Neurological Disorders and Stroke, NIH

Trial Design

Prospective, randomized, controlled, multicenter trial blinded with respect to surgeons, patients, and physicians performing outcome assessments, but not with respect to anesthesiologists.


  • Department of Anesthesia University of Iowa College of Medicine 200 Hawkins Dr Iowa City, IA