Intracerebral Hemorrhage Acutely Decreasing Arterial Pressure Trial "ICH ADAPT"

Completed

Phase 2 Results N/A

Update History

29 Feb '12
A location was updated in Calgary.
New
The overall status was removed for University of Calgary.
A location was updated in Edmonton.
New
The overall status was removed for University of Alberta.
A location was updated in Edmonton.
New
The overall status was removed for Grey Nuns Hospital.
A location was updated in Ottawa.
New
The overall status was removed for University of Ottawa.
6 Oct '11
The eligibility criteria were updated.
New
Inclusion Criteria: - Age ≥18 years - Acute primary ICH demonstrated with CT scan - Onset ≤ 24 h prior to randomization Exclusion Criteria: - Contraindication to BP reduction i.e., severe arterial stenosis or high-grade stenotic valvular heart disease - Indication for urgent BP reduction i.e., hypertensive encephalopathy, or aortic dissection - Definite evidence that the ICH is secondary to underlying cerebral or vascular pathology, i.e., AVM, aneurysm, tumour, trauma, vasculitis, or hemorrhagic transformation of an ischemic infarct - Previous ischemic stroke within 30 days of current event NB: Prior ICH is not an exclusion criterion - Planned surgical resection of hematoma NB: Extraventricular Drain placement is not an exclusion criterion - Contraindication to CT perfusion imaging (i.e. contrast allergy, metformin use or Creatinine >160 μmol/l)
Old
Inclusion Criteria: - Age ?18 years - Acute primary ICH demonstrated with CT scan - Onset ? 24 h prior to randomization Exclusion Criteria: - Contraindication to BP reduction i.e., severe arterial stenosis or high-grade stenotic valvular heart disease - Indication for urgent BP reduction i.e., hypertensive encephalopathy, or aortic dissection - Definite evidence that the ICH is secondary to underlying cerebral or vascular pathology, i.e., AVM, aneurysm, tumour, trauma, vasculitis, or hemorrhagic transformation of an ischemic infarct - Previous ischemic stroke within 30 days of current event NB: Prior ICH is not an exclusion criterion - Planned surgical resection of hematoma NB: Extraventricular Drain placement is not an exclusion criterion - Contraindication to CT perfusion imaging (i.e. contrast allergy, metformin use or Creatinine >160 ?mol/l)