Interventional Management of Stroke (IMS) III Trial "IMSIII"


Phase 3 Results

Summary of Purpose

The purpose of this study is to compare two different treatment approaches to recanalization started within 3 hours of symptom onset—combined intravenous (IV) and endovascular therapy and standard intravenous (IV) rt-PA alone. Trial Stopped: NINDS/NIH-DSMB recommended halting trial due to futility, no safety concerns.

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 19 November 2013.

1 Aug 2006 31 Jul 2006 1 Jul 2012 1 Apr 2013 1 Nov 2013 4 Jul 2013
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Allocation: Randomized
  • Masking: Open Label
  • Purpose: Treatment
  • Endpoint: Safety/Efficacy Study
  • Intervention: Parallel Assignment