International PFO Consortium


Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

- Age > 18 years
- Diagnosis of PFO established by transesophageal echocardiography (TEE)
- Ischemic stroke or transient ischemic attack within the previous 6 months
Exclusion Criteria
- Non-vascular origin of the neurological symptoms after brain imaging (CT scan or MRI)
- Comorbid condition that would interfere with the study
- Pregnancy
- History of intracranial bleeding, confirmed arterio-venous malformation, aneurysm or uncontrolled coagulopathy
- Contraindications for TEE, echocardiographic or iodine contrast media