International Cooperative Study of Extracranial/Intracranial Arterial Anastomosis "EC/IC Bypass Study"


Phase 3 Results


30-day surgical mortality and major stroke morbidity rates were 0.6% and 2.5%, respectively. The postoperative bypass patency rate was 96%. Nonfatal and fatal stroke occurred both more frequently and earlier in the patients operated on. Patients with severe middle-cerebral-artery stenosis and those with persistence of ischemic symptoms after and internal-carotid-artery occlusion fared substantially worse in the surgical group.