Influence of a Multi-parametric Optimization Strategy for General Anesthesia on Postoperative Morbidity and Mortality "OPTI-AGED"


Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

- All adult patients aged 75 years and over,
- presenting at least one of the following comorbidities: ischemic coronary disease; cardiac arrhythmia; congestive heart failure; peripheral vascular disease; dementia; stroke; chronic obstructive pulmonary disease; chronic respiratory failure; chronic alcohol abuse; active cancer; diabetes; chronic renal failure A comorbidity index will be measured by using the modified Charlson Comorbidity Index
- undergoing elective and emergency surgeries including : femoral head fracture, major intraperitoneal abdominal surgery lasting > 90 min (excluding elective cholecystectomy, abdominal wall surgery), vascular surgery (excluding venous surgery and fistula creation)
- Patient's or patient's relative signed consent form
- Affiliation to French social assurance system

Exclusion Criteria

- Acute heart failure and acute coronary syndrome
- Acute respiratory failure, pneumonia
- Septic shock
- Delirium
- Acute stroke
- Evolutive neuromuscular disorder
- Thoracic surgery, combined abdominal and thoracic surgery
- Surgery performed under exclusive regional anesthesia
- Patients under tutorship or curatorship
- Refusal to participate