IMplementation of an RCT to imProve Treatment With Oral AntiCoagulanTs in Patients With Atrial Fibrillation "IMPACT-AFib"

Enrolling by invitation

Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

1. Two or more diagnoses of AF (ICD-9 and/or 10 codes) at least one day apart and with at least one diagnosis within the last 12 months prior to the last date in the current approved data used for cohort identification
2. CHA₂DS₂-VASc score of 2 or greater
3. Medical and pharmacy insurance coverage of at least the prior year as identified via administrative claims databases of one of the participating data partners as of the date of randomization
4. Age 30 years or greater as of the last date in the current approved data used for cohort identification

Exclusion Criteria

1. Evidence of OAC medication fill during the 12 months prior to randomization (determined at randomization for the early intervention cohort and 12 months post-randomization for the delayed intervention cohort)
2. Conditions other than AF that require anticoagulation, including treatment of deep venous thrombosis, pulmonary embolism, or ever having had a mechanical prosthetic heart valve prior to the last date in the current approved data used for cohort identification
3. Pregnancy within 6 months of the last date in the current approved data used for cohort identification
4. Any known history of intracranial hemorrhage prior to the last date in the current approved data used for cohort identification
5. Hospitalization for bleeding within the last 6 months of the last date in the current approved data used for cohort identification
6. Patients with recent P2Y12 antagonist use (i.e. clopidogrel, prasugrel, ticlopidine, or ticagrelor within 90 days of the last date in the current approved data used for cohort identification