In hemiplegic, there is very little data on the impact of neurological deficit on the microarchitecture independent of bone mineral density and composition of the bone marrow. Rare studies have shown the relationship between some micro-architectural parameters and severity of neurological deficit. There is no study in humans on the evolution of the parameters of the microarchitecture assessed by 3D micro-tomography in the early phase of the installation of neurological deficits after stroke, in terms of a bearing bone, tibia, that a non-load bearing bones, radius.
Each patient must answer several questionnaires about their calcium intake and its ability to perform everyday tasks. They will also have 3 blood samples (15 ml each time), 3 measure of bone by 3D micro-tomography and 2 MRI examination. These examinations and sampling will take place after 30 days after stroke onset (except for MRI) and again after three months and six months after the stroke (the same day as the medical follow-up visit).
Trial Stopped: Inclusion rhythm too slow
- MRI and 3D CT scan Procedure
Intervention Desc: Measurement of bone microarchitecture at the legs and wrists by 3D CT Scan and measuring the proportion of fat in the imaging leg bone (MRI) ARM 1: Kind: Experimental Label: Patients Description: Patients who have experienced a vascular hemiplegia and accept bone measure by MRI and 3D CT scan
- Observation: Cohort
- Perspective: Prospective
- Sampling: Non-Probability Sample
Patient aged at least 30 who have experienced a vascular hemiplegia within 30 days before enrollment
|Type||Measure||Time Frame||Safety Issue|
|Primary||Bone volume / tissue volume||90 days||Yes|
|Secondary||intraosseous fat||90 days||Yes|
Biospecimen Retention:Samples With DNA - blood sample