Hypovitaminosis D in Neurocritical Patients

Not yet recruiting

Phase 2/3 Results N/A

Eligibility Criteria

Inclusion Criteria

- Patients >18 years of age
- Patients admitted to the neurosurgery or neurology services
- Patients admitted to a critical care unit
- Informed consent
- Expected to stay in the ICU for 48 hours or more
- Vitamin D deficiency (<20ng/mL)

Exclusion Criteria

- Patients where a vitamin D level was not drawn within 48 hours of admission
- Patients not randomized within 48 hours of admission
- Readmitted patients to the critical care unit
- Lack of informed consent
- Prior supplementation with vitamin D
- Severely impaired gastrointestinal function
- Other trial participation
- Pregnant or lactating women
- Hypercalcemia (total calcium of >10.6 mg/dL or ionized serum calcium of >5.4 mg/dL
- Tuberculosis history or clinical exam
- Sarcoidosis history or clinical exam
- Nephrolithiasis within the prior year
- Patients not deemed suitable for study participation (ie, psychiatric disease, living remotely from the clinic, or prisoner status)
- Pregnant or nursing women