Inclusion Criteria- Eligible for inclusion in the ICTuS 2/3 trial.
- Diagnosis of MCA stroke, confirmed by M1 or M2 proximal MCA occlusion on CT/MRI angiography.
Exclusion Criteria- Kidney dysfunction of such severity as to preclude routine administration of contrast media for CT/MRI angiography or perfusion imaging. Severe kidney dysfunction is defined by the American College of Radiology recommendations for use of contrast media.
- Known adverse reaction or allergy to such contrast media.