Hypercapnia to Prevent Secondary Ischemia in SAH "SAHCO2"


Phase 1 Results N/A

Summary of Purpose

Delayed cerebral vasospasm and secondary ischemic infarction are feared complications after aneurysmal subarachnoid hemorrhage (aSAH). To date, there is no effective therapy to prevent these ischemic complications. The arterial partial pressure of carbon dioxide (PaCO2) is one of the main determinants of cerebral blood flow (CBF) in healthy subjects. It is yet largely unknown, if and to what extent modulations of...

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 9 December 2014.

1 Jan 2013 20 Feb 2013 1 Feb 2014 1 Aug 2014 1 Dec 2014 Unavailable
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Masking: Single Blind (Subject)
  • Purpose: Treatment
  • Endpoint: Safety/Efficacy Study
  • Intervention: Single Group Assignment