To compare the effects of oral aspirin vs. high-dose IV unfractionated heparin (UFH) on the levels of inflammatory markers in blood plasma and the corresponding effect on neurological impairment.
- Heparin (acute stroke) Drug
Intervention Desc: Intravenous anticoagulant.
Prospective trial of 167 patients.
Patients received either 1000 I U/h IV UFH or 300 mg oral aspirin.
|Type||Measure||Time Frame||Safety Issue|
|Primary||Plasma levels of IL-6, IL-10, IL-4, TNF, sICAM-1, and sVCAM-1 at baseline and 48 h. Barthel Index (BI) score at 6 months.|