Heart Outcomes Prevention Evaluation "HOPE"


Phase N/A Results

Eligibility Criteria

Inclusion Criteria

Patients 55 years or older who had known vascular disease or diabetes in addition to one cardiac risk factor, such as hypertension, elevated cholesterol/LDL, a history of smoking, or microalbuminuria were eligible for the study.

Exclusion Criteria

Patients who had known low ejection fraction ( < 0.40), heart failure, uncontrolled hypertension, overt nephropathy, who had experienced an myocardial infarction or stroke within the past 4 weeks, or who were already taking ACE inhibitors or vitamin E were excluded from the study.