Heart Outcomes Prevention Evaluation-3 "HOPE-3"


Phase 4 Results N/A

Summary of Purpose

Heart disease and stroke are major causes of death and disability worldwide and are largely preventable. Cholesterol and blood pressure are major cardiovascular risk factors. Previous studies have shown that certain drugs can effectively and safely lower cholesterol and blood pressure and prevent heart attacks and strokes. Such studies have been conducted primarily in people who had already sustained a heart...

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 23 October 2017.

1 May 2007 2 May 2007 1 Dec 2015 1 Jan 2016 1 Oct 2017 Unavailable
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Allocation: Randomized
  • Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
  • Purpose: Prevention
  • Endpoint: Safety/Efficacy Study
  • Intervention: Factorial Assignment


  • 1st Contact: Jane Shannon hope3@cardio.on.ca 2nd Contact: Andrea Rathe hope3@cardio.on.ca Hamilton General Hospital Hamilton, Ontario, Canada, L8L 2X2