"GOLIATH" - General Or Local Anaestesia in Intra Arterial THerapy "GOLIATH"

Completed

Phase 3 Results N/A

Trial Description

Patients suffering a stroke with a large vessel occlusion is often treated intra veneous thrombolyse and on top of that also intra arterial therapy. It is unknown what form of anaestesia is best during intra arterial therapy. The investigators will randomize these patients between general anaestesia and local anaestesia. Outcome will be growth of the ischemic lesion as judged on an MRI scan.

Conditions

Interventions

  • Local anesthesia Procedure
    Intervention Desc: Conscious sedation
    ARM 1: Kind: Experimental
    Label: Local Anesthesia
    Description: The patients, who will receive local anesthesia/conscious sedation during intervention

Trial Design

  • Allocation: Randomized
  • Masking: Single Blind (Outcomes Assessor)
  • Purpose: Treatment
  • Endpoint: Efficacy Study
  • Intervention: Parallel Assignment

Outcomes

Type Measure Time Frame Safety Issue
Primary Growth of DWI lesion 48-72 hours No
Secondary Time from arrival to groin puncture and recanalization 1-2 hours No
Secondary Blood pressure during intervention 1-2 hours No
Secondary Modified Rankin Score 90 days No

Sponsors