Inclusion Criteria- Age 18 years or older
- Resident (6 months or longer) within 100 miles of University of Cincinnati.
- Fulfillment of the criteria for spontaneous ICH
- No evidence of trauma, brain tumor/metastases, hemorrhagic transformation of ischemic stroke or infectious processes as a cause of the hemorrhage.
- Ability of the patient or legal representative to provide consent for an interview, blood pressure determinations and DNA sampling.