Summary of Purpose
Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leucoencephalopathy (CADASIL) is an archetypal small vessel disease of the brain caused by dominant mutations in the NOTCH3 receptor. Cardinal vascular lesions include deposition of granular osmiophilic material (GOM) within the basal lamina of smooth muscle cells, progressive smooth muscle cell loss, and fibrosis of the media. Pathogenic...Read More →
The following dates are available for this trial. Trial information last updated on 7 January 2014.
|1 Feb 2014||3 Jan 2014||1 Aug 2016||1 Aug 2018||1 Jan 2014||Unavailable|
|Start Date||First Received||1st Completion||Completion||Verification||Results|
- Observation: Case-Only
- Perspective: Prospective
- Sampling: Non-Probability Sample