General Anesthesia for Endovascular Thrombectomy; A Pilot Study.

Enrolling by invitation

Phase N/A Results N/A

Update History

1 Apr '16
The eligibility criteria were updated.
New
Inclusion Criteria: - Acute ischemic stroke - Age 18 or greater - Onset (last seen well) time to treatment less than 12 hours - Disabling stroke defined as a baseline NIHSS > 5 at the time of treatment - Pre-stroke independent functional status in activities of daily living. Patient must be living in their own home, apartment or seniors lodge where no nursing care is required - Pre-enrollment non-intubated state based on acceptable GCS for the prospective Cohort - Small core proximal occlusion as confirmed by CT angiography (carotid, M1 MCA or M1 MCA equivalent) - Intention to initiate endovascular treatment within 60 minutes of baseline non-contrast CT - Sevoflurane used during thrombectomy - Appropriate consent provided Exclusion Criteria: - Baseline non-contrast CT reveals a moderate/large core defined as extensive early ischemic changes of ASPECTS 0-5 in the territory of symptomatic intracranial occlusion - Hemorrhagic stroke - Clinical history, past imaging or clinical judgment suggests that the intracranial occlusion is chronic - Intubated state based on GCS at any time prior to induction of general anesthesia for prospective cohort
Old
Inclusion Criteria: - Acute ischemic stroke - Age 18 or greater - Onset (last seen well) time to treatment less than 12 hours - Disabling stroke defined as a baseline NIHSS > 5 at the time of treatment - Pre-stroke independent functional status in activities of daily living. Patient must be living in their own home, apartment or seniors lodge where no nursing care is required - Pre-enrollment non-intubated state based on acceptable GCS for the prospective Cohort - Small core proximal occlusion as confirmed by CT angiography (carotid, M1 MCA or M1 MCA equivalent) - Intention to initiate endovascular treatment within 60 minutes of baseline non-contrast CT - Appropriate consent provided Exclusion Criteria: - Baseline non-contrast CT reveals a moderate/large core defined as extensive early ischemic changes of ASPECTS 0-5 in the territory of symptomatic intracranial occlusion - Hemorrhagic stroke - Clinical history, past imaging or clinical judgment suggests that the intracranial occlusion is chronic - Intubated state based on GCS at any time prior to induction of general anesthesia for prospective cohort
A location was updated in Saskatoon.
New
The overall status was removed for Royal University Hospital.