General Anesthesia for Endovascular Thrombectomy; A Pilot Study.

Enrolling by invitation

Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

- Acute ischemic stroke
- Age 18 or greater
- Onset (last seen well) time to treatment less than 12 hours
- Disabling stroke defined as a baseline NIHSS > 5 at the time of treatment
- Pre-stroke independent functional status in activities of daily living. Patient must be living in their own home, apartment or seniors lodge where no nursing care is required
- Pre-enrollment non-intubated state based on acceptable GCS for the prospective Cohort
- Small core proximal occlusion as confirmed by CT angiography (carotid, M1 MCA or M1 MCA equivalent)
- Intention to initiate endovascular treatment within 60 minutes of baseline non-contrast CT
- Sevoflurane used during thrombectomy
- Appropriate consent provided

Exclusion Criteria

- Baseline non-contrast CT reveals a moderate/large core defined as extensive early ischemic changes of ASPECTS 0-5 in the territory of symptomatic intracranial occlusion
- Hemorrhagic stroke
- Clinical history, past imaging or clinical judgment suggests that the intracranial occlusion is chronic
- Intubated state based on GCS at any time prior to induction of general anesthesia for prospective cohort