Field Administration of Stroke Therapy-Blood Pressure Lowering "FAST-BP"


Phase 2 Results N/A

Eligibility Criteria

Inclusion Criteria

1. Suspected stroke identified with Los Angeles Prehospital Stroke Screen
2. Age 40-80, inclusive
3. Last known well time within 2 hours of treatment initiation
4. Deficit present for > 15 minutes
5. Systolic blood pressure ≥180

Exclusion Criteria

1. Coma
2. Rapidly improving neurologic deficit
3. Pre-existing neurologic, psychiatric, or advanced systemic disease that would confound the neurological or functional outcome evaluations
4. Severe respiratory distress (O2 sat < 90% or respiratory rate < 12 or > 24)
5. Major head trauma in the last 24 hours
6. Recent stroke within prior 30 days
7. Use of erectile dysfunction therapies in the previous 12 hours
8. Use of type V phosphodiesterase inhibitors
9. Patient unable to give informed consent and no available legally authorized representative (LAR) to provide informed consent