Factor VII, Prothrombin Complex Concentrate, and Fresh Frozen Plasma in Warfarin-Related Intracranial Hemorrhage


Phase 1 Results N/A

Summary of Purpose

The purpose of this dose-ranging pilot study is to compare Recombinant Activated Factor VII, Prothrombin Complex Concentrate and Fresh Frozen Plasma (each starting at low doses with escalation if necessary) for the reversal of warfarin in the setting of acute intracranial hemorrhage. Trial Stopped: poor enrollment

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 22 November 2011.

1 Apr 2008 9 Oct 2008 1 Apr 2010 1 Apr 2010 1 Nov 2011 Unavailable
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Allocation: Non-Randomized
  • Masking: Open Label
  • Purpose: Treatment
  • Endpoint: Safety/Efficacy Study
  • Intervention: Parallel Assignment


  • Elaine Skalabrin, M.D. 801-581-6291