Extending Acute Stroke Trials to the Aerial Inter-hospital Transfer Setting "AIRDOC"

Completed

Phase N/A Results

Eligibility Criteria

Inclusion Criteria

- Age 18 years or older.
- Presumed Ischemic stroke or intracerebral hemorrhage within past 12 hours.
- NIH Stroke Scale (NIHSS) score >/=1 point.
- Negative pregnancy test (females < 50 years old).
- No pre-stroke disability (Rankin Scale Score 0-1).
- Patient evaluated for intravenous recombinant tissue Plasminogen Activator (rtPA) and intubation by the local physicians (if appropriate).

Exclusion Criteria

- Onset of symptoms > 12 hours or uncertain time of origin (if patient awakens with stroke, the time of onset will be the last time patient was normal).
- Reason for the transfer is to receive rtPA at the University of Iowa.
- Non-stroke etiology for symptoms.
- Temperature > 37.8 C.
- Systolic blood pressure < 100 mm Hg.
- Known allergy to ranitidine.
- White Blood Cell (WBC) > 10K.
- Hemoglobin < 9.0.
- Platelets < 100,000.
- Glucose < 60 or > 300 mg/dl.
- Current need for antibiotics.
- Terminal illness with expected survival < 3 months.
- Prison inmate or institutionalized individual.