EXTEND (International): Extending the Time for Thrombolysis in Emergency Neurological Deficits (International) "EXTEND"

Recruiting

Phase 3 Results N/A

Summary of Purpose

The primary hypothesis being tested in this trial is that ischaemic stroke patients selected with significant penumbral mismatch (according to imaging criteria) at 4.5 (or 3 hours depending on local guidelines) - 9 hours post onset of stroke or after 'wake up stroke' (WUS) will have improved clinical outcomes when given intravenous tissue plasminogen activator (tPA) compared to placebo.

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 21 September 2016.

1 Jun 2012 17 Apr 2012 1 Dec 2017 1 Dec 2017 1 Sep 2016 Unavailable
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Allocation: Randomized
  • Masking: Double Blind (Subject, Caregiver, Investigator)
  • Purpose: Treatment
  • Endpoint: Safety/Efficacy Study
  • Intervention: Parallel Assignment

Contacts