Evaluation of Memantine Versus Placebo on Ischemic Stroke Outcome "EMISO"

Not yet recruiting

Phase 3 Results N/A

Eligibility Criteria

Inclusion Criteria

- Presentation at first 24hrs of disease onset
- Confirmation of ischemic stroke in MCA territory by imaging.
- Accepted consent form

Exclusion Criteria

- Allergy history to memantine
- Stage 4 -5 renal failure base on Acute Kidney Injury Network criteria
- Moderate to severe hepatic failure (Child-Pugh criteria, grade B and C)
- History of epilepsy
- History of dementia
- History of memantine use in recent 6 months
- Pregnancy or breastfeeding
- Severe drug adverse effects