European Cooperative Acute Stroke Study "ECASS-I"

Completed

Phase 3 Results

Eligibility Criteria

Inclusion Criteria

Acute ischemic stroke (within 6 hours of onset) and moderate to severe neurologic deficit and without major early infarct signs on initial computed tomography (CT). Ages 18-80 years.

Exclusion Criteria

Severe hemispheric stroke syndrome, initial SSS >50-58 total points, patients already improving, preexisting disabling neurologic disease or preexisting concomitant medical conditions, spontaneous intracranial or intracerebral hemorrhage or major early infarct signs on CT scan.