European Carotid Surgery Trial "ECST"

Completed

Phase 3 Results

Results

The risk of major stroke or death was not reduced significantly and did not vary substantially with the severity of stenosis within 2-3 years of randomization, but there was an 11.6% benefit (determined by Kaplan-Meier estimate) from surgery after 3 years in patients with stenosis >greater than 80% in diameter. Variations in risk with age and sex were found to modify the results.