ESPRIT: European/Australasian Stroke Prevention in Reversible Ischaemia Trial


Phase 4 Results N/A

Eligibility Criteria

Inclusion Criteria

- Patients presenting in the participating hospitals with a TIA or non-disabling stroke of atherosclerotic origin
- Randomisation within 6 months after the TIA or minor stroke
- Modified Rankin scale of 3 or less

Exclusion Criteria

- (Contra)indication to, or intolerance to, anticoagulants, dipyridamole, or aspirin
- Disease expected to cause death within weeks or months
- Source of embolism in the heart
- Moderate or severe ischemic damage to the white matter of the brain (leukoaraiosis)
- Anemia, polycythemia, thrombocytosis, or thrombocytopenia
- Planned carotid endarterectomy
- Intracranial bleeding or cerebral tumour
- TIA or stroke caused by vasculitis, migraine, or dissection
- Severe hypertension
- Liver failure
- Pregnancy
- Chronic alcohol abuse