Enteral Nutrition and Glycemic Variability Neurological Intensive Care Unit Study "ANUS1014"


Phase 4 Results

Eligibility Criteria

Inclusion Criteria

- Patients aged between 18 and 89 years old
- Patients with critical illness including ischemic or hemorrhagic stroke, epidural/subdural bleeds and subarachnoid hemorrhage
- Patients who are expected to stay in the ICU for at least 5 days
- Hyperglycemia is not an inclusion criteria

Exclusion Criteria

- Patients who have received or will be treated with systemic corticosteroids.
- Patients who will be receiving high doses of propofol (>40 cc/hr)
- Patients with type 1 Diabetes
- Patients with sepsis or acute trauma
- Patients with an expected stay in the ICU of less than 4 days
- Patients who are unable to receive enteral nutrition or who have medical conditions precluding nutrition by the enteral route including allergies to formula components
- Pregnant and lactating patients
- Patients with prior history of gastroparesis
- Patients with acute kidney failure (creatinine > 2.5mg/dl)
- Patients with acute liver failure (bilirubin > 2.0 mg/dl)