Emergency Department Management of Sepsis Patients: A Goal-Oriented Non-Invasive Sepsis Trial "AGONIST"


Phase N/A Results N/A

Summary of Purpose

The purpose of this study is to determine whether the use of a 3-hour protocol utilizing non-invasive hemodynamic optimization treatment strategy results in better outcome and lower hospital costs in patients who present with severe bloodstream infections to the Emergency Department (ED).

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 23 September 2014.

1 Nov 2011 12 Oct 2011 1 Mar 2014 1 Mar 2014 1 Sep 2014 Unavailable
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Allocation: Randomized
  • Masking: Open Label
  • Purpose: Treatment
  • Endpoint: Efficacy Study
  • Intervention: Parallel Assignment


  • Win Sen Kuan, MBBS