Efficacy of the Non-invasive Brain Stimulation Techniques for Lower Limb Recovery in Stroke Patients

Not yet recruiting

Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

- For subjects receiving intervention:
1. Male or female aged 21-80 years;
2. First ever haemorrhagic or ischaemic subcortical stroke of 3-6 months prior to study enrolment;
3. Functional Ambulatory Category 3 (requires not more than minimal assistance for walking);
4. Be able to provide informed consent.
- For healthy subjects:
1. Male or female aged 21-80 years;
2. Physically healthy;
3. Be able to provide informed consent.
Exclusion criteria:
- For subjects receiving intervention:
1. Severe claustrophobia;
2. pregnancy;
3. cardiac pacemakers;
4. orthodontics (braces);
5. metal implant;
6. presence of other non MRI-compatible ferromagnetic implants;
7. history of epilepsy;
8. sensorimotor disturbance due to other causes other than stroke;
9. severe pain in the lower limbs affecting gait;
10. uncontrolled medical conditions including hypertension, diabetes mellitus and unstable angina;
11. major depression and a history of psychotic disorders (Subject with BDI score more than 30 will be excluded).
- For healthy subjects:
1. Cardiovascular diseases;
2. Diabetes mellitus;
3. Pulmonary diseases;
4. Smoker.