Efficacy of a Combined Linguistic/Communication Therapy in Acute Aphasia After Stroke "ORACLE"

Not yet recruiting

Phase N/A Results N/A

Trial Description

Linguistic training is traditionally the gold standard for rehabilitation of aphasia after stroke and efficacy criteria count early stage, intensity as well as personalized treatment. To date, no clear evidence showed a specific effect of any therapy in the acute phase of aphasia after stroke. This study aims to compare the effect of a combined therapy (linguistic/communication) versus a linguistic therapy on communication performance in patients in the acute phase of aphasia after a first stroke.

Detailed Description

Twenty to 25% of strokes cause aphasia. Speech and language therapy is the well-known standard treatment of aphasia after stroke although it is based on weak scientific evidence. To date, the efficacy criteria of aphasia rehabilitation are early stage, intensity as well as personalized treatment. Usually these patients receive in acute phase a linguistic training focused on the linguistic impairment. This approach is based on the cerebral plasticity postulate. However the superiority of this practice compared to other methods has never been shown. Moreover the benefit of the combination gathering linguistic treatment with communication treatment has to our knowledge never been studied.
In the present study investigators propose to compare the effect of a combined linguistic/communication rehabilitation versus a linguistic treatment. To do so, investigators will recruit patients with aphasia after a first stroke, in the acute phase. After a allocation to the " combined " and " linguistic " groups, all the patients will have a comprehensive language and neuropsychological assessment before and after 3 months of rehabilitation, and finally 6 months after the onset.
The "linguistic" group will have a rehabilitation only focused on linguistic processes whereas the "combined" group will have a linguistic training as well as communication training. The therapy will be personalized and the therapists will exclusively use standardized linguistic and/or communication toolboxes of rehabilitation containing dedicated activities.

Conditions

Interventions

  • Combined rehabilitation Other
    Intervention Desc: Linguistic training as well as communication training.
    ARM 1: Kind: Experimental
    Label: Combined rehabilitation
    Description: Linguistic training as well as communication training.
  • Linguistic rehabilitation Other
    Intervention Desc: Rehabilitation only focused on linguistic processes.
    ARM 1: Kind: Experimental
    Label: Linguistic rehabilitation
    Description: Rehabilitation only focused on linguistic processes.

Outcomes

Type Measure Time Frame Safety Issue
Primary Assessment of the communication performance. Month 3
Secondary Assessment of the linguistic performance. Month 3; Month 6
Secondary Assessment of the quality of life. Month 3; Month 6

Sponsors