Efficacy and Time Dependent Effects of tDCS Combined With MT for Rehabilitation After Subacute and Chronic Stroke

Not yet recruiting

Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

1. experienced a first-ever unilateral stroke with stroke onset ≥ 1 week;
2. UE-FMA score between 18 and 56
3. able to follow instructions to perform the tasks (Mini Mental State Examination ≥ 24)

Exclusion Criteria

1. Participants are currently involved in other rehabilitation or drug research trial(s);
2. have neurological or psychological disorders other than stroke;
3. have joint contracture or excessive spasticity of the paretic upper limb that prohibits them performing the tasks;
4. received Botulinum toxin injections 3 months prior to enrollment
5. have unstable cardiovascular status such as uncontrolled hypertension or New York Heart Association (NYHA) Class III/IV heart failure;
6. have contradictions to tDCS including a history of epilepsy, migraine headache, uncontrolled medical status, being pregnant, having a pacemaker, or metal implanted in their head or body
7. have a history of drug or alcohol abuse, skin lesions on the electrode sites, brain tumor, brain injury, arteriovenous malformation (AVM), had brain surgery, other brain diseases (such as intracranial hypertension or cerebral edema), or being not suitable for using tDCS by the physician's assessment.