Effects of Whole Body Vibration in Subacute Stroke Patients

Recruiting

Phase N/A Results N/A

Trial Description

The overall aim of the proposed study is to determine whether whole body vibration is beneficial in promoting bone turnover, physical fitness and neuromotor performance in patients with subacute stroke.

Detailed Description

Brief periods of Whole body vibration (WBV) have been shown to improve bone density in post-menopausal women and children with cerebral palsy. In addition to the apparent benefits on bone health, WBV has been shown to increase muscle strength, postural control, muscular blood flow and oxygen uptake in various populations. Therefore, WBV can potentially be used as a tool to improve muscle strength, balance, and cardiovascular performance, especially for those with relatively low level of functioning. Stroke patients are therefore possible beneficiaries of WBV, as they often demonstrate muscle weakness, balance deficits, and poor cardiovascular function, in addition to bone loss. Only one pilot study has examined the effects of WBV in stroke patients. Van Nes et al.showed that postural stability in chronic stroke patients is improved after a few minutes of WBV at 30Hz and 3mm amplitude. The overall aim of the proposed study is to determine whether whole body vibration is beneficial in promoting bone turnover, physical fitness and neuromotor performance in patients with subacute stroke.

Conditions

Interventions

  • Whole body vibration therapy Device
    Other Names: Jet-Vibe System (Danil SMC Co., Ltd., Seoul, Korea)
    Intervention Desc: In their regular physiotherapy sessions, the subjects in the experimental group will receive WBV (20-240Hz, 10-minute sessions, 1 session per day, 5 sessions per week). The vibration loading will be carried out using the Fit-Vibe System (Germany), which is a vibration platform that is capable of generating vertical vibration.
    ARM 1: Kind: Experimental
    Label: WBV
    Description: In their regular physiotherapy sessions, the subjects in the experimental group will receive whole body vibration therapy for a duration of 4 weeks during their stay in the Tung Wah Hospital.
  • Standing on the vibration platform but no vibration will be applied Other
    Intervention Desc: The subjects in this group will perform the same exercises on the vibration platform as in the experimental group for the same duration, but no vibration will be given.
    ARM 1: Kind: Experimental
    Label: CON
    Description: The subjects in this group will not receive whole body vibration therapy.

Trial Design

  • Allocation: Randomized
  • Masking: Single Blind (Outcomes Assessor)
  • Purpose: Treatment
  • Intervention: Parallel Assignment

Outcomes

Type Measure Time Frame Safety Issue
Primary Level of bone resorption marker CTx baseline, immediately after treatment, and 2-month follow-up No
Primary Level of bone formation marker, BSAP baseline, immediately after treatment, and 2-month follow-up No
Secondary Six minute walk test baseline, immediately after treatment, and 2-month follow-up No
Secondary Ankle arm index baseline, immediately after treatment, and 2-month follow-up No
Secondary Functional Ambulation category baseline, immediately after treatment, and 2-month follow-up No
Secondary Leg muscle strength (hand-held dynamometry) baseline, immediately after treatment, and 2-month follow-up No
Secondary Berg Balance Scale baseline, immediately after treatment, and 2-month follow-up No
Secondary Modified Ashworth Scale of Spasticity baseline, immediately after treatment, and 2-month follow-up No
Secondary Sensory threshold to light touch in the foot baseline, immediately after treatment, and 2-month follow-up No
Secondary Fugl-Meyer Motor Assessment baseline, immediately after treatment, and 2-month follow-up No

Sponsors