Effects of the Quantity of Repetitive Transcranial Magnetic Stimulation(rTMS) on the Recovery After Stroke

Terminated

Phase 2/3 Results N/A

Eligibility Criteria

Inclusion Criteria

- single mono-hemispheric ischemic or hemorrhagic stroke
- 1st onset stroke patient
- Upper extremity functional deficit attributable to acute stroke
- A stage of at least 3 on brunnström pre-treatment
- Written signed consent

Exclusion Criteria

- Multiple lesion
- Bilateral cortical lesion and motor problems
- Cerebellar, or brainstem lesions
- History of more than one stroke
- Uncontrolled medical problems, such as: cardiopulmonary disease, severe rheumatoid arthritis, active joint deformity of arthritic origin, active cancer, or renal disease;
- Increased intracranial pressure
- History of seizure confirmed by interview and medical chart review
- Any individual who is on medication which is known to lower seizure threshold
- Other conditions that increase the risk of side effects due to rTMS procedures: a metal plate or metal object in the skull or eye, intracardiac line, increased intracranial pressure, cardiac pacemaker, implanted medication pump, tricyclic antidepressants, neuroleptics, history of seizure in the immediate family
- An age of less than 20 years old
- Any current actively treated medical or surgical condition or neurological or psychiatric illness other than stroke
- Complications that would prevent participation in the intervention, such as severe pain and severe spasticity
- Inability to cooperate outcome measure-related task
- Severe language disturbances
- Serious cognitive deficits
- Non-vascular cause for the neurological symptoms other central nervous system
- Disorder or peripheral neuropathy of the upper extremity
- Taking medication which interrupt brain activity
- Women who are pregnant