Effects of tDCS Versus HD-tDCS for Stroke Rehabilitation "tDCS- Aphasia"


Phase 1 Results N/A

Trial Description

The purpose of this study is to assess the changes in language processing of patients with chronic aphasia after receiving non-invasive brain stimulation.Previous research using traditional transcranial direct current stimulation (tDCS) using 2 sponge electrodes has shown that persons with aphasia show more improvement after treatment when that treatment is accompanied by brain stimulation. Traditional tDCS has recently been modified to deliver current to more specific locations in the brain. This new delivery method is called high-definition tDCS (HD-tDCS). It is not known whether traditional tDCS (more diffuse current delivery) or HD-tDCS (more focal current delivery) will be the better approach for enhancing treatment outcomes. To answer this question, computerized speech-language treatment will be administered during the application of the different forms of brain stimulation.



  • HD-tDCS (Soterix) Device
    Other Names: Soterix Medical High-Definition M x N stimulator; Soterix Medical HDTargets
    Intervention Desc: Subjects will be given individualized dose (number of electrodes and electrode placement) through High-Definition electrodes to target fMRI determined targets
    ARM 1: Kind: Experimental
    Label: High-Definition tDCS
  • Transcranial Direct Current Stimulation (Neuroconn) Device
    Other Names: Neuroconn
    ARM 1: Kind: Experimental
    Label: Sponge tDCS

Trial Design

  • Allocation: Randomized
  • Masking: Single Blind
  • Purpose: Treatment
  • Intervention: Crossover Assignment


Type Measure Time Frame Safety Issue
No outcomes associated with this trial.