Effects of rTMS on Brain Activation in Aphasia


Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

- Aphasia due to unilateral left-hemisphere stroke
- Greater than 6 months post aphasia onset
- English as a first language
- No contraindications to MRI or TMS including:
- pregnancy
- presence of ferromagnetic substances in the head with the exception of dental fillings, stents or aneurysm clips documented to be MRI compatible
- presence of any implanted devices including cardiac pacemaker, implanted cardiac defibrillator, insulin pump, cochlear implant, or drug infusion device
- history of epilepsy; use of medications that are known to lower seizure threshold
- severe claustrophobia

Exclusion Criteria

- History for progressive neurological disease or premorbid language disorder
- Presence of severe motor speech disorder
- Drug or alcohol dependence, or significant mood or behavioral disorder that is not currently stable or medically managed