Effects of Respiratory Training on Respiratory and Functional Performance in Patients With Stroke

Not yet recruiting

Phase N/A Results N/A

Trial Description

The purpose of the research is to investigate the effects of respiratory training on respiratory and functional performance in patients with stroke.

Detailed Description

Stroke ranks third in the global cause of death, behind cancer and coronary heart disease. Stroke is also the third largest cause of death in Taiwan in 2014. Stroke patients in the course of exercise are in addition to muscle weakness and reduced endurance, but usually also accompanied by respiratory damage. From past studies have shown that stroke patients whose respiratory function has significant change, such as decreased respiratory muscle strength, reduced respiratory movement of the affected hemithorax, declined in maximum breathing pressure and decreased amplitude of diaphragmatic movements on the paralyzed side. But whether respiratory training can improve respiratory and functional performance of stroke patients, because of the limited research results could not be confirmed.

Conditions

Interventions

  • Respiratory training. Other
    Intervention Desc: breathing exercise.
    ARM 1: Kind: Experimental
    Label: RT (respiratory training) group
    Description: Besides traditional rehabilitation therapy, subjects also receive 12-week respiratory training.
  • Sham training. Other
    Intervention Desc: range of motion (ROM) exercise, stretching exercise or positioning exercise.
    ARM 1: Kind: Experimental
    Label: Control group
    Description: Besides traditional rehabilitation therapy, subjects receive 12-week sham training unrelated to respiratory function.

Trial Design

  • Allocation: Randomized
  • Masking: Double Blind (Subject, Caregiver, Outcomes Assessor)
  • Purpose: Treatment
  • Endpoint: Safety/Efficacy Study
  • Intervention: Parallel Assignment

Outcomes

Type Measure Time Frame Safety Issue
Primary Diaphragm Thickness. change from baseline diaphragm thickness at 12, 16, 24, 36 weeks. No
Primary Incidence of Pneumonia. change from baseline incidence of pneumonia at 12, 16, 24, 36 weeks. No
Primary Brunnstrom's motor recovery stages. change from baseline Brunnstrom's stages at 12, 16, 24, 36 weeks. No
Primary Stroke Rehabilitation Assessment of Movement scale; STREAM. change from baseline STREAM scores at 12, 16, 24, 36 weeks. No
Primary Stroke-Specific Quality of Life scale; SS-QOL. change from baseline SS-QOL scores at 12, 16, 24, 36 weeks. No
Primary Stroke Impact Scale; SIS 3.0. change from baseline SIS 3.0 scores at 12, 16, 24, 36 weeks. No
Primary Twelve-Minute Walk Test. change from baseline Twelve-Minute Walk Test scores at 12, 16, 24, 36 weeks. No
Primary Forced Vital Capacity (FVC) in liters. change from baseline FVC at 12, 16, 24, 36 weeks. No
Primary Vital Capacity (VC) in liters. change from baseline VC at 12, 16, 24, 36 weeks. No
Primary Forced Expiratory Volume at 1 second (FEV1) in liters. change from baseline FEV1 at 12, 16, 24, 36 weeks. No
Primary Ratio of FEV1 to FVC (FEV1/FVC). change from baseline FEV1/FVC ratio at 12, 16, 24, 36 weeks. No
Primary Forced Expiratory Flow rate 25-75% (FEF 25-75%) in liters per minute. change from baseline FEF 25-75% at 12, 16, 24, 36 weeks. No
Primary Peak Expiratory Flow Rate (PEFR) in liters per minute. change from baseline PEFR at 12, 16, 24, 36 weeks. No
Primary Maximum Inspiratory Pressure (PImax) in centimeters of water pressure (cmH2O). change from baseline PImax at 12, 16, 24, 36 weeks. No
Primary Maximum Expiratory Pressures (PEmax) in centimeters of water pressure (cmH2O). change from baseline PEmax at 12, 16, 24, 36 weeks. No
Primary Maximum Voluntary Ventilation (MVV) in liters per minute. change from baseline MVV at 12, 16, 24, 36 weeks. No

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