Effects of tDCS Versus HD-tDCS for Stroke Rehabilitation "tDCS- Aphasia"
Active, not recruiting
Phase 1 Results N/ATrial Description
The purpose of this study is to assess the changes in language processing of patients with chronic aphasia after receiving non-invasive brain stimulation.Previous research using traditional transcranial direct current stimulation (tDCS) using 2 sponge electrodes has shown that persons with aphasia show more improvement after treatment when that treatment is accompanied by brain stimulation. Traditional tDCS has recently been modified to deliver current to more specific locations in the brain. This new delivery method is called high-definition tDCS (HD-tDCS). It is not known whether traditional tDCS (more diffuse current delivery) or HD-tDCS (more focal current delivery) will be the better approach for enhancing treatment outcomes. To answer this question, computerized speech-language treatment will be administered during the application of the different forms of brain stimulation.
Conditions
Interventions
- HD-tDCS (Soterix) Device
Other Names: Soterix Medical High-Definition M x N stimulator; Soterix Medical HDTargets Intervention Desc: Subjects will be given individualized dose (number of electrodes and electrode placement) through High-Definition electrodes to target fMRI determined targets ARM 1: Kind: Experimental Label: High-Definition tDCS - Transcranial Direct Current Stimulation (Neuroconn) Device
Other Names: Neuroconn ARM 1: Kind: Experimental Label: Sponge tDCS
Trial Design
- Allocation: Randomized
- Masking: Single Blind
- Purpose: Treatment
- Intervention: Crossover Assignment
Outcomes
| Type | Measure | Time Frame | Safety Issue |
|---|---|---|---|
| No outcomes associated with this trial. | |||
Sponsors
Recruitment
- Gender: Both
- Minimum Age: 25 Years
- Accepts Healthy Volunteers: No
Principal Investigator
- Julius Fridriksson, PhD
University of South Carolina
