Effects of Combined Resistance and Aerobic Training vs Aerobic Training on Cognition and Mobility Following Stroke "TRI-RAvA"

Active, not recruiting

Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

- Clinical diagnosis of stroke (ischemic or hemorrhagic)
- Ability to walk at least 100 m independently with or without an assistive
- device with no severe limitations due to pain
- Living in the community at least 3 months post stroke (no upper limit)
- Stroke-related motor impairment score of 3-6 on the Chedoke-McMaster Stroke
- Assessment scale of the leg and/or foot
- Ability to provide informed consent

Exclusion Criteria

- Unstable angina or orthostatic blood pressure decrease of > 20 mmHg
- Resting hypertension (SBP > 160 mm Hg or DBP > 100 mm Hg)
- Diabetes related or other eye/vision complications (severe proliferative retinopathy)
- Cardiovascular morbidities which would limit exercise tolerance (e.g. heart failure, hypertrophic cardiomyopathy, horizontal or downsloping ST-segment depression > 2 mm, symptomatic aortic stenosis, complex arrhythmias)
- Musculoskeletal impairments which would preclude safe participation in exercise
- Cognitive and/or behavioral issues that would significantly limit participation in exercise testing and training, prior unrelated neurological disorders or psychiatric illness
- Severe communicative aphasia or comprehensive aphasia (as noted in clinical reports)
- Patients with anxiety disorder, claustrophobia, or pacemaker implantation will be excluded from brain imaging and perfusion measures
- Exposure to a similar or identical neuropsychological battery within <6 months
- Currently smoking