Effectiveness and Safety of Rhubarb for the Treatment of Patients Who Have Suffered From a Stroke

Active, not recruiting

Phase 2 Results N/A

Eligibility Criteria

Inclusion Criteria

- Occurrence of an acute ischemic stroke (between 9 and 72 h after onset) with a score of at least 6 on the National Institute of Health Stroke Scale (NIHSS), and patient age of at least 18 years.
- Have no pneumonia according to modified criteria of the U.S. Centers for Disease Control and Prevention (CDC)
- Consistent with the Constipation of Phlegm-Heat Accumulation type by Traditional Chinese Medicine (TCM) standard
- Patients or their representatives voluntarily take part in this study and signed the informed consent

Exclusion Criteria

- Cerebral hemorrhage, subarachnoid hemorrhage
- Transient ischemic attack(TIA)
- Proven cerebral embolism caused by tumor, Brain Trauma, cerebral parasitic disease, dysbolismus, fibrillation atrial resulted from rheumatic heart disease, coronary heart disease, and other heart diseases
- Clinical signs of infection on admission
- Pregnant or breast-feeding
- Allergic to rhubarb
- Preceding or ongoing antibiotic therapy within the last 24 h
- Participation in another interventional trial
- Immunosuppressant treatment within the last 30 days
- Combining severe clinical conditions such as liver, kidney, Hematopoietic System, endocrine system or psychological diseases