Effectiveness and Safety of Rhubarb for the Treatment of Patients Who Have Suffered From a Stroke

Active, not recruiting

Phase 2 Results N/A

Trial Description

This study will determine if rhubarb will reduced the incidence of pneumonia and improved recovery from an acute stroke. The study is designed to look at both infection rate and overall recovery and recovery of motor function, for example muscle strength and coordination.

Conditions

Interventions

  • Placebo Drug
    Intervention Desc: 14 days of placebo
    ARM 1: Kind: Experimental
    Label: 2
  • Rhubarb Drug
    Intervention Desc: 14 days of rhubarb
    ARM 1: Kind: Experimental
    Label: 1
    Description: rhubarb

Trial Design

  • Allocation: Randomized
  • Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
  • Purpose: Prevention
  • Endpoint: Safety/Efficacy Study
  • Intervention: Parallel Assignment

Outcomes

Type Measure Time Frame Safety Issue
Primary The lung infection rate within 14 days after stroke onset 14 days No
Secondary Global disability on modified Rankin scale 90 days No
Secondary NIH stroke scale 90 days No
Secondary Barthel Index 90 days No
Secondary Death rate 90 days No
Secondary Syndrome score by Traditional Chinese Medicine (TCM) standard 90 days No
Secondary Changes in laboratory indexes as safety assessment, including red blood cell(RBC), white blood cell(WBC), platelet(PLT), alanine transaminase (ALT), aspartate transaminase (AST), blood urea nitrogen (BUN), creatinine(Cr) in blood samples, etc. 90 days Yes

Sponsors