Effect of Transcranial Magnetic Stimulation on Recovery of Upper Limb Among Stroke Survivors

Active, not recruiting

Phase N/A Results N/A

Update History

27 Feb '16
The eligibility criteria were updated.
New
Inclusion Criteria: --≥18 years of age - Ability to give informed consent - An unilateral ischemic stroke of onset 6-36 months prior to the study - No other known brain abnormalities by medical history or by MRI - Affected upper limb function of score 2-6 in Chedoke Arm and Hand Inventory - Enrolled or planned to be enrolled in occupational therapy at Kessler Institute for Rehabilitation as an outpatient Exclusion Criteria: - More than one stroke (Transient Ischemic Attack not a reason for exclusion) Neurological conditions other than stroke (brain tumor, Parkinson's disease, etc) - History of epilepsy or unprovoked seizures - Family history of epilepsy (father, mother, children, siblings with diagnosis of epilepsy) - Implanted medical devices (pacemakers, defibrillators, medical pump, implanted brain stimulator, aneurysm clip, carotid or cerebral stents, central venous catheter, cochlear implant, internal hearing aids) - Damaged skin or skull of head - Excessive spasticity of upper limb as indicated by Modified Ashworth Spasticity Scale >2/4 - Recent injection of antispastic medications (Botulinum toxin, phenol) of the last 3 months or scheduled such injection during the study period - Severe sensory deficits as measured by a score of 2 on item 8 of the National Institute of Health (NIH) stroke scale - Severe aphasia as measured by a score of ≥2 on item 9 of NIH stroke scale - Being determined to be medically unstable by a physician - Being pregnant or trying to become pregnant - Past or current alcohol abuse, illicit drug use, or significant mental illness (schizophrenia, major depression, manic disorders) - Working with metal currently or in the past - Tattoo with metal based ink on the head or neck - Unable to answer the questionnaires in the consent form correctly
Old
Inclusion Criteria: --≥18 years of age - Ability to give informed consent - An unilateral ischemic stroke of onset 6-36 months prior to the study - No other known brain abnormalities by medical history or by MRI - Affected upper limb function of score 2-6 in Chedoke Arm and Hand Inventory - Enrolled or planned to be enrolled in occupational therapy at Kessler Institute for Rehabilitation as an outpatient Exclusion Criteria: - More than one stroke (Transient Ischemic Attack not a reason for exclusion) Neurological conditions other than stroke (brain tumor, Parkinson's disease, etc) - History of epilepsy or unprovoked seizures - Family history of epilepsy (father, mother, children, siblings with diagnosis of epilepsy) - Implanted medical devices (pacemakers, defibrillators, medical pump, implanted brain stimulator, aneurysm clip, carotid or cerebral stents, central venous catheter, cochlear implant, internal hearing aids) - Damaged skin or skull of head - Excessive spasticity of upper limb as indicated by Modified Ashworth Spasticity Scale >2/4 - Recent injection of antispastic medications (Botulinum toxin, phenol) of the last 3 months or scheduled such injection during the study period - Severe sensory deficits as measured by a score of 2 on item 8 of the National Institute of Health (NIH) stroke scale - Severe aphasia as measured by a score of ≥2 on item 9 of NIH stroke scale - Being determined to be medically unstable by a physician - Being pregnant or trying to become pregnant - Past or current alcohol abuse, illicit drug use, or significant mental illness (schizophrenia, major depression, manic disorders) - Working with metal currently or in the past - Tattoo with metal based ink on the head or neck - Unable to answer the questionnaires in the consent form correctly
A location was updated in West Orange.
New
The overall status was removed for Kessler Foundation.
12 Sep '13
The eligibility criteria were updated.
New
Inclusion Criteria: --≥18 years of age - Ability to give informed consent - An unilateral ischemic stroke of onset 6-36 months prior to the study - No other known brain abnormalities by medical history or by MRI - Affected upper limb function of score 2-6 in Chedoke Arm and Hand Inventory - Enrolled or planned to be enrolled in occupational therapy at Kessler Institute for Rehabilitation as an outpatient Exclusion Criteria: - More than one stroke (Transient Ischemic Attack not a reason for exclusion) Neurological conditions other than stroke (brain tumor, Parkinson's disease, etc) - History of epilepsy or unprovoked seizures - Family history of epilepsy (father, mother, children, siblings with diagnosis of epilepsy) - Implanted medical devices (pacemakers, defibrillators, medical pump, implanted brain stimulator, aneurysm clip, carotid or cerebral stents, central venous catheter, cochlear implant, internal hearing aids) - Damaged skin or skull of head - Excessive spasticity of upper limb as indicated by Modified Ashworth Spasticity Scale >2/4 - Recent injection of antispastic medications (Botulinum toxin, phenol) of the last 3 months or scheduled such injection during the study period - Severe sensory deficits as measured by a score of 2 on item 8 of the National Institute of Health (NIH) stroke scale - Severe aphasia as measured by a score of ≥2 on item 9 of NIH stroke scale - Being determined to be medically unstable by a physician - Being pregnant or trying to become pregnant - Past or current alcohol abuse, illicit drug use, or significant mental illness (schizophrenia, major depression, manic disorders) - Working with metal currently or in the past - Tattoo with metal based ink on the head or neck - Unable to answer the questionnaires in the consent form correctly
Old
Inclusion Criteria: ≥18 years of age Ability to give informed consent An unilateral ischemic stroke of onset 6-36 months prior to the study No other known brain abnormalities by medical history or by MRI Affected upper limb function of score 2-6 in Chedoke Arm and Hand Inventory Being enrolled or planned to be enrolled in occupational therapy at Kessler Institute for Rehabilitation as an outpatient Exclusion Criteria: More than one stroke (Transient Ischemic Attack not a reason for exclusion) Neurological conditions other than stroke (brain tumor, Parkinson's disease, etc) History of epilepsy or unprovoked seizures Family history of epilepsy (father, mother, children, siblings with diagnosis of epilepsy) Implanted medical devices (pacemakers, defibrillators, medical pump, implanted brain stimulator, aneurysm clip, carotid or cerebral stents, central venous catheter, cochlear implant, internal hearing aids) Damaged skin or skull of head Excessive spasticity of upper limb as indicated by Modified Ashworth Spasticity Scale >2/4 Recent injection of antispastic medications (Botulinum toxin, phenol) of the last 3 months or scheduled such injection during the study period Severe sensory deficits as measured by a score of 2 on item 8 of the National Institute of Health (NIH) stroke scale48 Severe aphasia as measured by a score of ≥2 on item 9 of NIH stroke scale48 Being determined to be medically unstable by a physician Being pregnant or trying to become pregnant Past or current alcohol abuse, illicit drug use, or significant mental illness (schizophrenia, major depression, manic disorders) Working with metal currently or in the past Tattoo with metal based ink on the head or neck Unable to answer the questionnaires in the consent form correctly