Effect of Transcranial Magnetic Stimulation on Recovery of Upper Limb Among Stroke Survivors

Active, not recruiting

Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

--≥18 years of age
- Ability to give informed consent
- An unilateral ischemic stroke of onset 6-36 months prior to the study
- No other known brain abnormalities by medical history or by MRI
- Affected upper limb function of score 2-6 in Chedoke Arm and Hand Inventory
- Enrolled or planned to be enrolled in occupational therapy at Kessler Institute for Rehabilitation as an outpatient

Exclusion Criteria

- More than one stroke (Transient Ischemic Attack not a reason for exclusion) Neurological conditions other than stroke (brain tumor, Parkinson's disease, etc)
- History of epilepsy or unprovoked seizures
- Family history of epilepsy (father, mother, children, siblings with diagnosis of epilepsy)
- Implanted medical devices (pacemakers, defibrillators, medical pump, implanted brain stimulator, aneurysm clip, carotid or cerebral stents, central venous catheter, cochlear implant, internal hearing aids)
- Damaged skin or skull of head
- Excessive spasticity of upper limb as indicated by Modified Ashworth Spasticity Scale >2/4
- Recent injection of antispastic medications (Botulinum toxin, phenol) of the last 3 months or scheduled such injection during the study period
- Severe sensory deficits as measured by a score of 2 on item 8 of the National Institute of Health (NIH) stroke scale
- Severe aphasia as measured by a score of ≥2 on item 9 of NIH stroke scale
- Being determined to be medically unstable by a physician
- Being pregnant or trying to become pregnant
- Past or current alcohol abuse, illicit drug use, or significant mental illness (schizophrenia, major depression, manic disorders)
- Working with metal currently or in the past
- Tattoo with metal based ink on the head or neck
- Unable to answer the questionnaires in the consent form correctly