Effect of Nimodipine on Memory After Cerebral Infarction

Completed

Phase N/A Results

Trial Description

To determine whether nimodipine given 7-14 days after cerebral infarction improves memory.

Interventions

  • Nimodipine (NimotopĀ®)Drug
    Intervention Desc: Calcium channel blocker (L-type calcium channels)

Trial Design

Single-blind, randomized, controlled trial of 100 patients.

Patient Involvement

Patients were randomized to receive oral nimodipine 90 mg daily for 12 weeks, or no drug.

Outcomes

Type Measure Time Frame Safety Issue
Primary Mini-Mental State Examination (MMSE) and Fuld Object-Memory Evaluation (FOME) at baseline, 6 weeks, and 12 weeks.